1698041

Job Description Summary

The Manager, Supply Chain Operations position is a key role within our strategic plan for Supply Chain management. This individual must be able to must be able to operate within a dynamic Team, fast-paced, start-up and operational environment. Must have a good understanding of Supply chain fundamentals including: Demand and Supply Management, inventory planning, and materials resource planning. Must be organized with close attention to detail, analytical and able to make data-driven decisions, have good communication and negotiation skills, and have a proven ability to work cross functionally.

Your Responsibilities:

  • Maintain, develop, and update MRP and capacity planning model for multiple value streams from raw material through labeled drug product
  • Work with internal and external teams, suppliers, contract manufacturers, and clinical teams to ensure material availability for production processes and finished goods inventory to support ongoing clinical and sales demand.
  • Support the S/C&OP planning process using inputs and creating dashboards from the value stream models
  • Perform ad hoc scenario planning as necessary using models and dashboards to inform and support S/C&OP process
  • Maintain, create, and develop metrics/KPIs used by the supply chain team
  • Support execution and cross-functional accountability throughout Mirati supply chain
  • Provide back-up support for supply chain functions including shipping, receiving, material handling and other duties as assigned
  • Collaborate with internal customers and provide a high level of customer service, including recommending solutions, resources, and alternative supply options
  • Ensure and promote compliance to Company and Supply Chain policies and procedures
  • Complete special projects and other duties as assigned

What is Required:

  • Bachelors degree in supply chain, data science, or related field
    • MBA preferred
  • 5-8+ years of supply chain experience
  • Demonstrated organizational skills and ability to balance multiple priorities simultaneously
  • Proficient with Microsoft Office and expert level Excel skills
  • Experience with Great Plains/Microsoft Dynamics 365 and Microsoft BI preferred
  • Applied knowledge of forecasting, MRP, supply chain and inventory management
  • Able to influence others and manage conflict
  • Ability to self-direct and take constructive action in ambiguous situations
  • Extremely high standards of excellence
  • Analytical with a methodical approach to problem solving

About Mirati Therapeutics

Mirati Therapeutics is a late-stage biotechnology company whose mission is to discover, design and deliver breakthrough therapies to transform the lives of patients with cancer and their loved ones. The company is relentlessly focused on bringing forward therapies that address areas of high unmet need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer. Mirati is using its scientific expertise to develop novel solutions in two registration-enabling programs: adagrasib (MRTX849), an investigational small molecule, potent and selective KRAS G12C inhibitor, as monotherapy and in combination with other agents, and sitravatinib, an investigational spectrum-selective inhibitor of receptor tyrosine kinases in combination with checkpoint inhibitor therapies. Mirati is also advancing its differentiated preclinical portfolio, including MRTX1133, an investigational KRAS G12D inhibitor, and other oncology discovery programs. Unified for patients, Mirati’s vision is to unlock the science behind the promise of a life beyond cancer.

For more information about Mirati Therapeutics, visit us at Mirati.com or follow us on LinkedIn.

Why Join?

At Mirati, we have an unapologetic and relentless focus on our mission to transform the lives of patients with cancer and their loved ones. Patients and their families motivate us to work smarter, faster and better. We are driven by the knowledge that our efforts can one-day deliver life-saving therapies for the people who need us most. Urgency, open-mindedness, accountability and collaboration ground our work. These shared values are central to who we are, what we do and how we do it.

Our people fuel our success. They are fearless and passionate in their daily pursuit of our mission. We are committed to continuing to create a company and experience that attracts and keeps the best people. When you want your days to count and the work you do to matter, discovering and delivering potentially life-changing therapies is more than a job, it’s the chance to be part of something bigger.

We believe diverse professional experiences and an inclusive culture can drive better outcomes for patients. We want employees to be authentic and use their perspectives to contribute to our mission in a meaningful way.

Mirati cultivates an environment where:

  • An entrepreneurial attitude is encouraged
  • Our people are empowered to speak up, embrace the gray and achieve solutions
  • Diverse experiences are an important of part making the best decisions
  • We laugh and have fun as a work family

No matter the role, we are unified by our passion for helping patients, and are inspired by a single vision to unlock the science behind the promise of a life beyond cancer. Together, we own Mirati’s success.

Learn more at Mirati.com/careers

Mirati is an Equal Opportunity Employer (EOE) we celebrate diverse experiences without regard to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic information, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.

1630945

Job Description Summary

This position is responsible for the development and maintenance of investigational material supply plans and strategies for early and late stage small and large molecule development compounds throughout the life of a clinical study. As the clinical supply chain’s primary input to cross functional teams (CMC team, project team, study team, etc.), the role liaises with the cross functions to proactively assemble key program/protocol attributes necessary to generate approvable clinical supply strategies and plans. With an advanced understanding of clinical protocol design and the risks associated with clinical supply chain activities, the CSPM is a key driver of the decisions that impact a clinical study’s supply strategy by being a vocal member on teams while representing the clinical supply chain. The role will also work closely with vendors and internal support resources to ensure the on-time execution of activities in order to meet supply milestones.

Your Responsibilities:

  • Responsible for review of clinical protocols and the development of supply chain strategies that ensure alignment with the clinical study plan, milestones, and the clinical development plan.
  • Through a knowledge of clinical study design, the CSPM contributes to and influences protocol content and supply strategy to minimize drug supply and patient compliance risks.
  • Engages cross functional peers to drive key decisions required to develop supply strategies and study objectives.
  • Directs the planning and execution of clinical supply packaging, labeling, and logistics events with vendors to ensure timely delivery to support clinical studies.
  • Working with vendors and internal resources, develops the strategy for comparators, labels, packaging, distribution and returns strategies.
  • Provides input to the development of investigational product related content in study documents including investigator meeting documents, protocols, and pharmacy manuals
  • Responsible to raise and communicate supply chain risks that may impact initial and on-going supply continuity, while presenting risk mitigation strategies to enable continuity.
  • Contributes to the development of IRT system user requirements (URS) and user acceptance testing while ensuring the system manages drug supply effectively.
  • Responsible for monitoring/facilitating drug supply events within IRT from study start-up through study closure
  • Develops demand/supply forecast and communicates plans to key stakeholders (CMC, Manufacturing, etc.).
  • Responsible to develop clinical supply budget and monitoring expenditures against the supply budget.

What is Required:

Degrees:

  • BS/BA degree in related discipline and five to eight plus years of clinical supply project management experience preferred.
  • Professional Project Management certification is also desirable

Experience:

  • Proficient knowledge of protocol interpretation, IRT URS development and UAT.
  • Understanding of clinical supply interdependencies within the drug development process and clinical study execution.
  • Demonstrated experience developing working with clinical supply vendors.
  • Knowledge of temperature-controlled distribution, import/export and logistics
  • Broad knowledge of and experience with cGMP, GDP and GCP standards and guidance documents such as Annex 13.
  • Broad knowledge of CMC, manufacturing, Quality Assurance, Clinical operational processes
  • Demonstrated experience in global clinical supply forecasting and planning, packaging and labeling operations, IRT and clinical trial design

Skills:

  • Proficiency with standard Microsoft applications (MS Word, MS Excel, MS PowerPoint, MS Project, MS Visio).
  • Demonstrated ability in communicating, influencing and driving decisions while a member of cross functional teams supporting clinical studies.
  • Ability to effectively work in complex, dynamic and fast paced drug development environment.

About Mirati Therapeutics

Mirati Therapeutics is a late-stage biotechnology company whose mission is to discover, design and deliver breakthrough therapies to transform the lives of patients with cancer and their loved ones. The company is relentlessly focused on bringing forward therapies that address areas of high unmet need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer. Mirati is using its scientific expertise to develop novel solutions in two registration-enabling programs: adagrasib (MRTX849), an investigational small molecule, potent and selective KRAS G12C inhibitor, as monotherapy and in combination with other agents, and sitravatinib, an investigational spectrum-selective inhibitor of receptor tyrosine kinases in combination with checkpoint inhibitor therapies. Mirati is also advancing its differentiated preclinical portfolio, including MRTX1133, an investigational KRAS G12D inhibitor, and other oncology discovery programs. Unified for patients, Mirati’s vision is to unlock the science behind the promise of a life beyond cancer.

For more information about Mirati Therapeutics, visit us at Mirati.com or follow us on LinkedIn.

Why Join?

At Mirati, we have an unapologetic and relentless focus on our mission to transform the lives of patients with cancer and their loved ones. Patients and their families motivate us to work smarter, faster and better. We are driven by the knowledge that our efforts can one-day deliver life-saving therapies for the people who need us most. Urgency, open-mindedness, accountability and collaboration ground our work. These shared values are central to who we are, what we do and how we do it.

Our people fuel our success. They are fearless and passionate in their daily pursuit of our mission. We are committed to continuing to create a company and experience that attracts and keeps the best people. When you want your days to count and the work you do to matter, discovering and delivering potentially life-changing therapies is more than a job, it’s the chance to be part of something bigger.

We believe diverse professional experiences and an inclusive culture can drive better outcomes for patients. We want employees to be authentic and use their perspectives to contribute to our mission in a meaningful way.

Mirati cultivates an environment where:

  • An entrepreneurial attitude is encouraged
  • Our people are empowered to speak up, embrace the gray and achieve solutions
  • Diverse experiences are an important of part making the best decisions
  • We laugh and have fun as a work family

No matter the role, we are unified by our passion for helping patients, and are inspired by a single vision to unlock the science behind the promise of a life beyond cancer. Together, we own Mirati’s success.

Learn more at Mirati.com/careers

Mirati is an Equal Opportunity Employer (EOE) we celebrate diverse experiences without regard to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic information, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.

1638871

Job Description Summary

The Vice President, Supply Chain will be responsible for the development and implementation the clinical and commercial supply chain strategy for Mirati Therapeutics. This position reports to our SVP of Technical Operations.

As a member of Mirati’s leadership team, this role is an opportunity to bring seasoned experience and skills to build a world-class supply chain organization. This is a strategic role that supports clinical and commercial supply and spans US and OUS territories. In close collaboration with the SVP, Technical Operations you will also serve as the lead Supply Chain point of contact to all external stakeholders including collaboration partners and contract service providers and to key internal stakeholders from Development, Commercial, Quality, Finance/Accounting and Legal.

This individual will be responsible for leading Mirati’s Supply Chain strategy. You will develop and execute the company’s Supply Chain strategy in support of the corporate development strategy and the company’s deep and growing development pipeline.

This is a unique opportunity to help guide the organization through our evolution as a U.S.-based research and development organization to a global commercial-stage biotech with potential for multiple products launching beyond 2022.

Your Responsibilities:

  • Develop, lead, plan and execute a Supply Chain strategy for new product candidates, in partnership with the SVP, Technical Operations to attain rapid regulatory approvals.
  • Designs, develops and secures effective commercial supply chains
  • Establish, manage, and maintain a knowledge base of current and emerging supply chain practices and best practices, and interpret and communicate relevant issues within the organization.
  • Continually assess the needs of the organization and build world class Supply Chain Organization to meet the Company’s growing business needs.
  • Develops departmental policies and oversees and/or authorizes their implementation.
  • Leads or manages the work of others by providing guidance to subordinates or teams based on organizational goals and company policy. Develops team members to their full potential.
  • Establishes clear expectations, sets priorities, focuses resources, and delegates effectively. Closely monitors progress and proactively addresses issues and obstacles. Flexible and responsive to change; creative problem-solving skills. Highly decisive and action-oriented. When needed, strong individual contributor, with a hands-on style.
  • Establish and manage the relationship with Contract Manufacturing Organizations (CMOs) for production and release of commercial
  • Report manufacturing results within and outside the
  • Control and reduce costs related to raw material, direct material, and indirect material and services commodities by understanding of the competitive landscape for various commodities and applying global market intelligence to commodity strategies and supplier negotiations.
  • Develop and manage Supply Chain budget
  • Assures supply chain operations are in compliance with regulatory standards and corporate policies
  • Lead JMC activities on behalf of Mirati with commercialization/partner(s)
  • May fill addition leadership assignments within Technical Operations such as departmental representative as assigned.

What is Required:

  • MS degree in related discipline or BS with MBA and 18+ years of related experience. APICS or ISM certification is preferred.
  • Proven success building and leading a supply chain function
  • Proven track record of successes in managing clinical and commercial supply chains for small molecule drug products (oncology preferred).
  • Expert knowledge of the supply chain processes and applicable global laws and regulations.
  • Natural leader with a positive management style, combined with superior communication skills and unwavering ethics and integrity.
  • Strong interpersonal skills with demonstrated ability to connect, collaborate and build relationships across all levels and functions and establish credibility with leaders and key external stakeholders
  • Management and leadership skills, with ability to lead matrixed, cross-functional work teams
  • Strong oral and written communication skills with ability to communicate effectively at all levels and present complex and/or new ideas both internally and with external stakeholders
  • Experience interacting effectively with the Executive Leadership Team
  • Strong analytical skills, problem solving ability and presentation skills required.
  • Flexibility and ability to prioritize and manage multiple tasks simultaneously.
  • Ability to work in a fast-paced environment, as well as a proven track record of working effectively in diverse teams involving multi-functional disciplines.
  • Proficient with broad use computer applications such as MS Office and specialized supply chain applications as needed for job.
  • Ability to travel up to 40% domestically and internationally

About Mirati Therapeutics

Mirati Therapeutics is a late-stage biotechnology company whose mission is to discover, design and deliver breakthrough therapies to transform the lives of patients with cancer and their loved ones. The company is relentlessly focused on bringing forward therapies that address areas of high unmet need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer. Mirati is using its scientific expertise to develop novel solutions in two registration-enabling programs: adagrasib (MRTX849), an investigational small molecule, potent and selective KRAS G12C inhibitor, as monotherapy and in combination with other agents, and sitravatinib, an investigational spectrum-selective inhibitor of receptor tyrosine kinases in combination with checkpoint inhibitor therapies. Mirati is also advancing its differentiated preclinical portfolio, including MRTX1133, an investigational KRAS G12D inhibitor, and other oncology discovery programs. Unified for patients, Mirati’s vision is to unlock the science behind the promise of a life beyond cancer.

For more information about Mirati Therapeutics, visit us at Mirati.com or follow us on LinkedIn.

Why Join?

At Mirati, we have an unapologetic and relentless focus on our mission to transform the lives of patients with cancer and their loved ones. Patients and their families motivate us to work smarter, faster and better. We are driven by the knowledge that our efforts can one-day deliver life-saving therapies for the people who need us most. Urgency, open-mindedness, accountability and collaboration ground our work. These shared values are central to who we are, what we do and how we do it.

Our people fuel our success. They are fearless and passionate in their daily pursuit of our mission. We are committed to continuing to create a company and experience that attracts and keeps the best people. When you want your days to count and the work you do to matter, discovering and delivering potentially life-changing therapies is more than a job, it’s the chance to be part of something bigger.

We believe diverse professional experiences and an inclusive culture can drive better outcomes for patients. We want employees to be authentic and use their perspectives to contribute to our mission in a meaningful way.

Mirati cultivates an environment where:

  • An entrepreneurial attitude is encouraged
  • Our people are empowered to speak up, embrace the gray and achieve solutions
  • Diverse experiences are an important of part making the best decisions
  • We laugh and have fun as a work family

No matter the role, we are unified by our passion for helping patients, and are inspired by a single vision to unlock the science behind the promise of a life beyond cancer. Together, we own Mirati’s success.

Learn more at Mirati.com/careers.

Mirati is an Equal Opportunity Employer (EOE) we celebrate diverse experiences without regard to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic information, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.

1639380

Job Description Summary

We are looking for a seasoned Director of Strategic Sourcing to support our rapidly growing Clinical Programs and preparations for commercial launch of multiple products. This position will drive the establishment and “best practices” of the Strategic Sourcing function within our Technical Operations organization, This position will be responsible for the development and implementation of the Supply Chain’s Strategic Sourcing policies, processes and procedures, including Sourcing Strategy, Vendor Qualification, Sourcing Process, Vendor Selection and Strategic Supplier Relationship Management.

Your Responsibilities:

  • Developing and leading a Strategic Sourcing Center of Excellence
  • Establishing the Strategic Sourcing function, creating the necessary procedures, processes, building and developing the required team including coaching and skill development
  • Ensuring timely execution and completion of Supply Chain sourcing events
  • Driving improvements and efficiencies resulting in added value to the organization
  • Fostering collaborative relationships with internal stakeholders (e.g. Clinical Operations, Development, Regulatory, Quality, Operations, Finance, etc.) and understanding organizational needs
  • Establishing a strategic governance supplier relationship management program to ensure supplier partnerships are properly developed, managed, and monitored
  • Facilitating and executing supplier governance meetings and operating reviews
  • Understanding the marketplace, obtaining relevant Market Intelligence that not only ensures effective and educated decision making but also provides strategic forward knowledge enabling future sourcing strategy development. Including understanding and monitoring critical supply markets, anticipated industry developments and future innovative service offerings
  • Managing day to day sourcing operations, ensure competitive landscape through RFQs/RFPs, proposal analysis, selection decisions, , and negotiating contracts
  • Establishing and manage strategic and effective relationships with strategic suppliers, establishing meaningful metrics, driving innovation, identifying and mitigating risk and generating value creation
  • Overseeing contracting process within Technical Operations
  • Managing key strategic accounts, as assigned

What is Required:

Required Qualifications:

  • BA or BS degree
  • 12+ experience in Strategic Sourcing, Supplier Management and / or Category Management
  • Experience with International / Global Sourcing and ContractsProven leadership in developing strategic relationships and evolving supply networks
  • Management experience and team development
  • Excellent written and oral communication and presentation skills
  • Strong problem solving, decision making, planning, analytical and project management skills

Preferred Qualification:

  • CPSM, CPM or other Sourcing / Procurement related certifications
  • Master’s Degree
  • 8+ years supervisory experience
  • Proven value delivery and stakeholder satisfaction

About Mirati Therapeutics

Mirati Therapeutics is a late-stage biotechnology company whose mission is to discover, design and deliver breakthrough therapies to transform the lives of patients with cancer and their loved ones. The company is relentlessly focused on bringing forward therapies that address areas of high unmet need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer. Mirati is using its scientific expertise to develop novel solutions in two registration-enabling programs: adagrasib (MRTX849), an investigational small molecule, potent and selective KRAS G12C inhibitor, as monotherapy and in combination with other agents, and sitravatinib, an investigational spectrum-selective inhibitor of receptor tyrosine kinases in combination with checkpoint inhibitor therapies. Mirati is also advancing its differentiated preclinical portfolio, including MRTX1133, an investigational KRAS G12D inhibitor, and other oncology discovery programs. Unified for patients, Mirati’s vision is to unlock the science behind the promise of a life beyond cancer.

For more information about Mirati Therapeutics, visit us at Mirati.com or follow us on LinkedIn.

Why Join?

At Mirati, we have an unapologetic and relentless focus on our mission to transform the lives of patients with cancer and their loved ones. Patients and their families motivate us to work smarter, faster and better. We are driven by the knowledge that our efforts can one-day deliver life-saving therapies for the people who need us most. Urgency, open-mindedness, accountability and collaboration ground our work. These shared values are central to who we are, what we do and how we do it.

Our people fuel our success. They are fearless and passionate in their daily pursuit of our mission. We are committed to continuing to create a company and experience that attracts and keeps the best people. When you want your days to count and the work you do to matter, discovering and delivering potentially life-changing therapies is more than a job, it’s the chance to be part of something bigger.

We believe diverse professional experiences and an inclusive culture can drive better outcomes for patients. We want employees to be authentic and use their perspectives to contribute to our mission in a meaningful way.

Mirati cultivates an environment where:

  • An entrepreneurial attitude is encouraged
  • Our people are empowered to speak up, embrace the gray and achieve solutions
  • Diverse experiences are an important of part making the best decisions
  • We laugh and have fun as a work family

No matter the role, we are unified by our passion for helping patients, and are inspired by a single vision to unlock the science behind the promise of a life beyond cancer. Together, we own Mirati’s success.

Learn more at Mirati.com/careers

Mirati is an Equal Opportunity Employer (EOE) we celebrate diverse experiences without regard to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic information, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.

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