1755458

Job Description Summary

The Associate Director, Quality Metrics will report directly to the Head of Quality Assurance. This individual will be responsible for the development, execution, and implementation of the Quality Metrics program at Mirati. The Associate Director, Quality Metrics will ensure that all aspects of the operational business (including contracted vendors) comply with cGMP regulatory requirements (US/EU/ROW), the Mirati Quality Manual and Policies, and site procedures. The ideal candidate will have a strong quality assurance and quality systems background, experience with small molecules, and regulatory inspections. In addition, excellent verbal and written communications skills are required.

Your Responsibilities

Reporting to the Head of Quality Assurance, the Associate Director, Quality Metrics will have the following responsibilities. These may include but are not limited to:

  • Develop, execute, and implement a robust and compliant Quality Metrics program which meets all regulatory requirements and according to Mirati Corporate Quality Manual and relevant SOPs.
  • Establish internal process for collection of data and information flow from all key quality systems and sources. This also encompasses relevant CMO data and information.
  • Author and present quarterly quality metrics reports to senior management. This includes data interpretation of analytical, manufacturing, compliance and regulatory data and drawing conclusions from data.
  • Verify the consistency of existing processes and highlight any trends. Provide a documented review of key quality indicators with support of SMEs to determine the need for changes in product or process specifications, manufacturing, or quality procedures and ensuring alignment with filing.
  • Establish review and verification process with key SMEs for the evaluation of trends and determination of CAPAs for inclusion in quarterly metrics reviews.
  • Ensure follow-up and closure of all CAPAs identified and linkage to other quality systems (e.g. Deviation trending reports, etc.)
  • Identify continuous improvement opportunities based on metrics and drive consistency through the process to align with Mirati’s standard processes and quality systems.
  • Manage multiple projects and ongoing work activities within the function typically involving cross-functional representatives.
  • Complete annual assessment of health of Mirati Quality Metrics Program
  • Interface with Regulatory Agencies in audits, track, and report metrics for all internal auditing activities.
  • Other duties as assigned.

What is Required

  • Bachelor’s Degree in Chemistry, Engineering, Biology, Manufacturing Management, or related scientific discipline required.
  • 8-10+ years of experience in pharma/biopharma industry required.
  • Experience in QA and/or Manufacturing and/QC, experience dealing with Regulatory compliance.
  • Experience in problem solving, process improvement, negotiations and supervision.

About Mirati Therapeutics

Mirati Therapeutics is a late-stage biotechnology company whose mission is to discover, design and deliver breakthrough therapies to transform the lives of patients with cancer and their loved ones. The company is relentlessly focused on bringing forward therapies that address areas of high unmet need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer. Mirati is using its scientific expertise to develop novel solutions in two registration-enabling programs: adagrasib (MRTX849), an investigational small molecule, potent and selective KRAS G12C inhibitor, as monotherapy and in combination with other agents, and sitravatinib, an investigational spectrum-selective inhibitor of receptor tyrosine kinases in combination with checkpoint inhibitor therapies. Mirati is also advancing its differentiated preclinical portfolio, including MRTX1133, an investigational KRAS G12D inhibitor, and other oncology discovery programs. Unified for patients, Mirati’s vision is to unlock the science behind the promise of a life beyond cancer.

For more information about Mirati Therapeutics, visit us at Mirati.com or follow us on Twitter and LinkedIn.

Why Join?

At Mirati, we have an unapologetic and relentless focus on our mission to transform the lives of patients with cancer and their loved ones. Patients and their families motivate us to work smarter, faster and better. We are driven by the knowledge that our efforts can one-day deliver life-saving therapies for the people who need us most. Urgency, open-mindedness, accountability and collaboration ground our work. These shared values are central to who we are, what we do and how we do it.

Our people fuel our success. They are fearless and passionate in their daily pursuit of our mission. We are committed to continuing to create a company and experience that attracts and keeps the best people. When you want your days to count and the work you do to matter, discovering and delivering potentially life-changing therapies is more than a job, it’s the chance to be part of something bigger.

We believe diverse professional experiences and an inclusive culture can drive better outcomes for patients. We want employees to be authentic and use their perspectives to contribute to our mission in a meaningful way.

Mirati cultivates an environment where:

  • An entrepreneurial attitude is encouraged
  • Our people are empowered to speak up, embrace the gray and achieve solutions
  • Diverse experiences are an important of part making the best decisions
  • We laugh and have fun as a work family

No matter the role, we are unified by our passion for helping patients, and are inspired by a single vision to unlock the science behind the promise of a life beyond cancer. Together, we own Mirati’s success.

Learn more at Mirati.com/careers.

Mirati is an Equal Opportunity Employer (EOE) we celebrate diverse experiences without regard to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic information, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.

1755469

Job Description Summary

Reporting to the Head of Quality Assurance; the Director, GXP Auditing will be responsible for managing the GXP Audit function by ensuring compliance to applicable regulations, guidelines, and operating procedures. The Director, GXP Auditing will plan and conduct GXP audits, assess audit findings, and prepare and distribute reports of findings to senior management and contracted vendors as appropriate. Provide consultation in interpretation of regulations, guidelines, policies, and procedures.

Your Responsibilities

The Director, GXP Auditing will have the following responsibilities. These may include but are not limited to:

  • Develops and implements quality audit plans and maintains GXP Audit Schedule
  • Conducts and/or coordinates GxP compliance audits of third parties/vendors, (i.e. Routine or Non-Routine, pre-clinical, toxicology sites, clinical sites, manufacturing sites, etc.) in accordance with QA (Quality Assurance) risk-based processes
  • Assesses compliance of vendors processes against ICH (International Conference of Harmonization), applicable government agency regulations/ guidelines, as well as company policies, procedures and industry standards; applies comprehensive working knowledge of Quality Assurance, regulations and auditing
  • Evaluates audit findings and prepare and distribute reports to senior management
  • Monitors responses to audit observations and formulation of corrective action plans
  • Ensures corrective actions are taken to bring QA observations to closure as applicable
  • Provide interpretation and consultation to project teams on regulations, guidelines, compliance status, and policies and procedures
  • Coordinates Periodic Internal Audit Assessments
  • Assists the Head of Quality in host audits and/or inspections; Ensures proper conduct of partner-initiated audits and mock regulatory inspections, and assist in regulatory facility inspections
  • Manage vendor qualification audits in Veeva QMS and provides support in relation to the audit lifecycle
  • Develop, revise, implement and adhere to Quality Assurance department policies and procedures
  • Lead/collaborate/support in QA initiatives/projects for quality, process improvements
  • Evaluate policies and procedures for compliance with applicable regulations/guidelines and provide recommendations to management for continuous process improvements
  • JustOther duties as assigned

What is Required

  • Bachelor’s Degree in Chemistry, Engineering, Biology, Manufacturing Management, or related scientific discipline required.
  • 10+ years of experience in pharma/biopharma industry required.
  • 4+ years previous clinical/nonclinical Quality Assurance experience conducting a broad range of audits.
  • Experience in QA and/or Manufacturing and/QC, experience dealing with Regulatory compliance.
  • Experience in problem solving, process improvement, negotiations and supervision.

About Mirati Therapeutics

Mirati Therapeutics is a late-stage biotechnology company whose mission is to discover, design and deliver breakthrough therapies to transform the lives of patients with cancer and their loved ones. The company is relentlessly focused on bringing forward therapies that address areas of high unmet need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer. Mirati is using its scientific expertise to develop novel solutions in two registration-enabling programs: adagrasib (MRTX849), an investigational small molecule, potent and selective KRAS G12C inhibitor, as monotherapy and in combination with other agents, and sitravatinib, an investigational spectrum-selective inhibitor of receptor tyrosine kinases in combination with checkpoint inhibitor therapies. Mirati is also advancing its differentiated preclinical portfolio, including MRTX1133, an investigational KRAS G12D inhibitor, and other oncology discovery programs. Unified for patients, Mirati’s vision is to unlock the science behind the promise of a life beyond cancer.

For more information about Mirati Therapeutics, visit us at Mirati.com or follow us on Twitter and LinkedIn.

Why Join?

At Mirati, we have an unapologetic and relentless focus on our mission to transform the lives of patients with cancer and their loved ones. Patients and their families motivate us to work smarter, faster and better. We are driven by the knowledge that our efforts can one-day deliver life-saving therapies for the people who need us most. Urgency, open-mindedness, accountability and collaboration ground our work. These shared values are central to who we are, what we do and how we do it.

Our people fuel our success. They are fearless and passionate in their daily pursuit of our mission. We are committed to continuing to create a company and experience that attracts and keeps the best people. When you want your days to count and the work you do to matter, discovering and delivering potentially life-changing therapies is more than a job, it’s the chance to be part of something bigger.

We believe diverse professional experiences and an inclusive culture can drive better outcomes for patients. We want employees to be authentic and use their perspectives to contribute to our mission in a meaningful way.

Mirati cultivates an environment where:

  • An entrepreneurial attitude is encouraged
  • Our people are empowered to speak up, embrace the gray and achieve solutions
  • Diverse experiences are an important of part making the best decisions
  • We laugh and have fun as a work family

No matter the role, we are unified by our passion for helping patients, and are inspired by a single vision to unlock the science behind the promise of a life beyond cancer. Together, we own Mirati’s success.

Learn more at Mirati.com/careers.

Mirati is an Equal Opportunity Employer (EOE) we celebrate diverse experiences without regard to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic information, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.

1688133

Job Description Summary

  • Contribute to development of robust oncology protocols using novel designs (i.e. Adaptive, Baysean, BOIN)
  • Develop and validate applied research strategies relevant to advance existing assets, sponsored trials, and clinical research collaborations
  • Conduct multi-disciplinary research to decipher disease properties, using both published and novel computational approaches, to impact research and translational path for patient benefit
  • Deliver novel hypotheses for patient benefit using innovative and adaptive trial designs
  • Investigate key data assets across the company and leverage applied research strategies and patient data to empower data-driven decisions
  • Design and analyze key datasets from patient samples before and after treatment to inform and advance research
  • Provide predictive, original, and actionable insights into therapeutic mechanisms of action for existing and novel therapies
  • Participation in oversight of written and verbal scientific communications
  • Presentation of methods, results, and conclusions
  • Review medical literature and related new technologies
  • Work seamlessly across Research and Development teams with shared objectives in a mutually productive fashion.

What is Required

  • Advanced degree in scientific discipline, operations research, computational biology or other relevant field, PhD preferred
  • Minimum of 10 years oncology clinical development experience including master protocols, basket studies and RWE
  • Demonstrated practical experience in developing and managing oncology protocols with novel designs (i.e. Adaptive, Baysean, BOIN)
  • Direct experience using analytics to predict, control and monitor clinical trial performance
  • Extensive knowledge of application and analysis of synthetic control arms
  • Strong applied knowledge in predictive analytics, clinical statistics, or machine learning within the field of data science.
  • Track record of peer-reviewed publications in relevant scientific journals
  • Deep expertise in algorithmic implementation, statistical programming, and data manipulation
  • In depth knowledge of domestic and international regulatory guidelines and ICH/GCP
  • Highly developed collaboration and communication skills, be capable of explaining complex models to a wide audience
  • Proven expertise in the proactive identification of issues which may impact clinical programs coupled with the ability to contribute to solutions affecting cross-functional matrix teams

About Mirati Therapeutics

Mirati Therapeutics is a late-stage biotechnology company whose mission is to discover, design and deliver breakthrough therapies to transform the lives of patients with cancer and their loved ones. The company is relentlessly focused on bringing forward therapies that address areas of high unmet need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer. Mirati is using its scientific expertise to develop novel solutions in two registration-enabling programs: adagrasib (MRTX849), an investigational small molecule, potent and selective KRAS G12C inhibitor, as monotherapy and in combination with other agents, and sitravatinib, an investigational spectrum-selective inhibitor of receptor tyrosine kinases in combination with checkpoint inhibitor therapies. Mirati is also advancing its differentiated preclinical portfolio, including MRTX1133, an investigational KRAS G12D inhibitor, and other oncology discovery programs. Unified for patients, Mirati’s vision is to unlock the science behind the promise of a life beyond cancer.

For more information about Mirati Therapeutics, visit us at Mirati.com or follow us on LinkedIn.

Why Join?

At Mirati, we have an unapologetic and relentless focus on our mission to transform the lives of patients with cancer and their loved ones. Patients and their families motivate us to work smarter, faster and better. We are driven by the knowledge that our efforts can one-day deliver life-saving therapies for the people who need us most. Urgency, open-mindedness, accountability and collaboration ground our work. These shared values are central to who we are, what we do and how we do it.

Our people fuel our success. They are fearless and passionate in their daily pursuit of our mission. We are committed to continuing to create a company and experience that attracts and keeps the best people. When you want your days to count and the work you do to matter, discovering and delivering potentially life-changing therapies is more than a job, it’s the chance to be part of something bigger.

We believe diverse professional experiences and an inclusive culture can drive better outcomes for patients. We want employees to be authentic and use their perspectives to contribute to our mission in a meaningful way.

Mirati cultivates an environment where:

  • An entrepreneurial attitude is encouraged
  • Our people are empowered to speak up, embrace the gray and achieve solutions
  • Diverse experiences are an important of part making the best decisions
  • We laugh and have fun as a work family

No matter the role, we are unified by our passion for helping patients, and are inspired by a single vision to unlock the science behind the promise of a life beyond cancer. Together, we own Mirati’s success.

Learn more at Mirati.com/careers.

Mirati is an Equal Opportunity Employer (EOE) we celebrate diverse experiences without regard to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic information, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.

1712942

Job Description Summary

As Sr. Manager of Statistical Programming, you will manage programming activities to ensure they are appropriately planned and executed for all assigned clinical studies. This role will interact with Biostatistics, Clinical Data Management, Medicals, Clinical Operations and Regulatory to design, write, validate and document SAS programs in accordance with company, industry, and regulatory requirements; you will play key role in developing, implementing and evaluating statistical programming standards and processes; serve as expert on CDISC data standard; develops global macros to improve efficiency and capacity of statistical programming function. The position will provide you opportunities to demonstrate your skills, influences, make your contributions as well as for leadership growth.

Your Responsibilities

Manage and lead all programming activities in a drug development program; lead the development of timelines and resource plan

  • Anticipates resource needs and works with management to ensure adequate long-term resource allocation within a drug development program
  • Participates in the development of overall objectives and influences long-term goals of the organizations
  • Provides technical and project management leadership in SAS programs and applications designed to analyze and report complex oncology trial
  • Work with biometric team to develop submission strategy and lead programming team to create submission package.
  • Act as principal programmer leading/performing hands-on programming activities to support clinical development, CSR, submissions, publications and presentations
  • Create/review programming plan, specifications for datasets and TLFs. Expert level of understanding of CDISC standards, including SDTM and ADaM models and experienced in implementing these models.
  • Develop and validate SAS programs to produce high quality deliverables for in-house and outsourced projects in compliance with company and regulatory requirements. The deliverables include SDTM and ADaM datasets, define.xml, tables, listings and figures.
  • Manage CRO programming activities; review and validate deliverables produced by CROs, independently provide solutions to issues raised by CROs
  • Familiarization with ICH guidelines, advanced knowledge of submission requirements and standards, ensure that statistical programming deliverables are in compliance with regulatory requirements, industry and company standards.
  • Having expert level of SAS programming expertise, develop global macro tools that can improve overall efficiency and capacity of programming function
  • Lead the development, implementation and continuous improvement of programming process and standard
  • May lead and supervise programming staffs
  • Effectively communicate in a project team environment, within department, among functional groups and external collaborators

What is Required

  • Minimum of BS required in Statistics, Computer Science, Life Sciences or other related fields
  • BS with 8+ years or MS with 6+ years of SAS programming experience in drug development in CRO or pharma/biotech company; experience with R language is a plus
  • Strong written and verbal communication skills
  • Oncology and submission experience preferred

About Mirati Therapeutics

Mirati Therapeutics is a late-stage biotechnology company whose mission is to discover, design and deliver breakthrough therapies to transform the lives of patients with cancer and their loved ones. The company is relentlessly focused on bringing forward therapies that address areas of high unmet need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer. Mirati is using its scientific expertise to develop novel solutions in two registration-enabling programs: adagrasib (MRTX849), an investigational small molecule, potent and selective KRAS G12C inhibitor, as monotherapy and in combination with other agents, and sitravatinib, an investigational spectrum-selective inhibitor of receptor tyrosine kinases in combination with checkpoint inhibitor therapies. Mirati is also advancing its differentiated preclinical portfolio, including MRTX1133, an investigational KRAS G12D inhibitor, and other oncology discovery programs. Unified for patients, Mirati’s vision is to unlock the science behind the promise of a life beyond cancer.

For more information about Mirati Therapeutics, visit us at Mirati.com or follow us on LinkedIn.

Why Join?

At Mirati, we have an unapologetic and relentless focus on our mission to transform the lives of patients with cancer and their loved ones. Patients and their families motivate us to work smarter, faster and better. We are driven by the knowledge that our efforts can one-day deliver life-saving therapies for the people who need us most. Urgency, open-mindedness, accountability and collaboration ground our work. These shared values are central to who we are, what we do and how we do it.

Our people fuel our success. They are fearless and passionate in their daily pursuit of our mission. We are committed to continuing to create a company and experience that attracts and keeps the best people. When you want your days to count and the work you do to matter, discovering and delivering potentially life-changing therapies is more than a job, it’s the chance to be part of something bigger.

We believe diverse professional experiences and an inclusive culture can drive better outcomes for patients. We want employees to be authentic and use their perspectives to contribute to our mission in a meaningful way.

Mirati cultivates an environment where:

  • An entrepreneurial attitude is encouraged
  • Our people are empowered to speak up, embrace the gray and achieve solutions
  • Diverse experiences are an important of part making the best decisions
  • We laugh and have fun as a work family

No matter the role, we are unified by our passion for helping patients, and are inspired by a single vision to unlock the science behind the promise of a life beyond cancer. Together, we own Mirati’s success.

Learn more at Mirati.com/careers.

Mirati is an Equal Opportunity Employer (EOE) we celebrate diverse experiences without regard to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic information, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.

1746643

Job Description Summary

Mirati is looking for a Senior Safety Systems Associate to join our growing team. This position is primarily responsible for performing all pharmacovigilance (PV) Systems activities for both the US & Globally. Responsibilities include maintenance of Argus & PVQ systems, supporting PV Operations and performing audit related activities. The individual will be responsible to maintain all updates on Industry/ Regulatory standards for PV systems. He / She will be responsible for implementation of new PV applications to support PV Operations, Signal Detection and Risk Management activities. The successful candidate will have the ability to work independently and also as a part of the team. The successful candidate will have the ability to work in a dynamic, changing environment to meet corporate and patient needs.

Your Responsibilities

  • Collaborate with database hosting vendor to implement system changes (e.g., study/product configurations, user access requests, etc.,) as needed to support PV business needs.
  • Collaborate with database hosting vendor to upgrade MedDRA and WHO Drug dictionaries for Argus Safety Database as per PV requirements.
  • Responsible for tracking all managed service tickets and ensuring timely and adequate follow-up from the database hosting vendor.
  • Perform UAT testing as needed for any PV system.
  • Perform Disaster Recovery activities for Argus and PVQ on a periodic basis.
  • Provide overview training on Argus safety database to new PV staff and perform user account maintenance review on a periodic basis.
  • Liaise with partners to implement and support XML transmission activities.
  • Configure and retrieve data listing requests to support expedited reporting, monthly safety reviews, SAE reconciliation activities, periodic reports and ad-hoc requests, as needed.
  • Management of Argus Safety database upgrades including interfacing with the database hosting vendor and Mirati IT & Quality Assurance.
  • Setting up Electronic E2B gateways for submissions to Health Authorities.
  • Partnering with Mirati Data Management to setup electronic SAE reporting from the clinical database (RAVE).
  • Support internal audit/inspection activities by providing data listings from Argus/PVQ.
  • Ensuring pre-approval inspection readiness regarding all necessary Argus/PVQ documents.
  • Preparation and management of necessary SOPs related to Argus/PVQ.
  • Selection and implementation of data visualization and analytics software (e.g., Spotfire) for signal detection activities.
  • Perform routine regulatory intelligence activities related to changes in impacting PV systems.

What is Required

  • At least 5 years’ experience in a Safety systems role in the pharmaceutical industry with focus on knowledge of Argus console configurations and maintenance.
  • Bachelor’s degree or higher in life science or computing degree
  • Knowledge of PV systems and processes (Argus, Cognos etc.)
  • Knowledge of GCP and ICH Guidelines
  • Proficient in Microsoft Office products (including Word and Excel)
  • Experience with SQL and/or PL/SQL required
  • Knowledge of GxP software applications
  • Knowledge of Data visualization and analytics software

About Mirati Therapeutics

Mirati Therapeutics is a late-stage biotechnology company whose mission is to discover, design and deliver breakthrough therapies to transform the lives of patients with cancer and their loved ones. The company is relentlessly focused on bringing forward therapies that address areas of high unmet need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer. Mirati is using its scientific expertise to develop novel solutions in two registration-enabling programs: adagrasib (MRTX849), an investigational small molecule, potent and selective KRAS G12C inhibitor, as monotherapy and in combination with other agents, and sitravatinib, an investigational spectrum-selective inhibitor of receptor tyrosine kinases in combination with checkpoint inhibitor therapies. Mirati is also advancing its differentiated preclinical portfolio, including MRTX1133, an investigational KRAS G12D inhibitor, and other oncology discovery programs. Unified for patients, Mirati’s vision is to unlock the science behind the promise of a life beyond cancer.

For more information about Mirati Therapeutics, visit us at Mirati.com or follow us on Twitter and LinkedIn.

Why Join?

At Mirati, we have an unapologetic and relentless focus on our mission to transform the lives of patients with cancer and their loved ones. Patients and their families motivate us to work smarter, faster and better. We are driven by the knowledge that our efforts can one-day deliver life-saving therapies for the people who need us most. Urgency, open-mindedness, accountability and collaboration ground our work. These shared values are central to who we are, what we do and how we do it.

Our people fuel our success. They are fearless and passionate in their daily pursuit of our mission. We are committed to continuing to create a company and experience that attracts and keeps the best people. When you want your days to count and the work you do to matter, discovering and delivering potentially life-changing therapies is more than a job, it’s the chance to be part of something bigger.

We believe diverse professional experiences and an inclusive culture can drive better outcomes for patients. We want employees to be authentic and use their perspectives to contribute to our mission in a meaningful way.

Mirati cultivates an environment where:

  • An entrepreneurial attitude is encouraged
  • Our people are empowered to speak up, embrace the gray and achieve solutions
  • Diverse experiences are an important of part making the best decisions
  • We laugh and have fun as a work family

No matter the role, we are unified by our passion for helping patients, and are inspired by a single vision to unlock the science behind the promise of a life beyond cancer. Together, we own Mirati’s success.

Learn more at Mirati.com/careers.

Mirati is an Equal Opportunity Employer (EOE) we celebrate diverse experiences without regard to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic information, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.

1746692

Job Description Summary

The Senior Drug Safety Associate will provide support for Mirati Safety Operations including QC/ QA of Individual Case Safety Reports (ICSRs), SAE reconciliation, signal detection, literature surveillance, and support other Pharmacovigilance activities as needed.

Your Responsibilities

  • Responsible for day-to-day Quality review of ICSR’s including Narratives, Product coding, Medical coding, other case fields and for any possible discrepancies with the related source documents.
  • Review and update follow-up queries as appropriate.
  • Review regulatory reports required for ICSR submissions on a case by case basis.
  • Perform SAE reconciliation with appropriate CRO data management personnel and Mirati team members as applicable.
  • Address any case-processing related queries during CRO/partner reconciliation.
  • Review, update and maintain Data Entry Guidelines as applicable.
  • Serve as the Compound lead to address any questions related to SAE reconciliation activities. Provide SAE reconciliation metrics/compliance updates during study meetings.
  • Assist with Literature surveillance activities.
  • Perform User acceptance testing in the safety database development environment for data-entry related changes before rolling to production.
  • Support signal detection and evaluation activities in accordance with SOPs and guidelines.
  • Develop and maintain Pharmacovigilance SOPs/work instructions as required.
  • Ensure audit preparedness and support regulatory inspections.
  • Under the direction/review of senior PV staff, participate in other PV and Risk Management activities, as needed.

What is Required

  • Bachelors’ Degree or higher nursing, pharmacy or related health care field (required).
  • At least 7 – 8 years’ experience in a drug safety/pharmacovigilance case processing role with minimum 4 years’ experience as ICSR Quality Reviewer.
  • Relevant experience in the oncology therapeutic area, preferred.
  • Experience needed with drug safety database (ARGUS, preferred).
  • Experience with coding verbatim AE terms, medical history, laboratory data, and products using MedDRA and WHO-Drug dictionaries.
  • Knowledge and experience with case-processing guidelines as per local and Global GVP requirements.
  • Strong communication and narrative writing skills.
  • Knowledge with US/Global safety reporting and regulatory compliance.
  • Competent in Microsoft Word, PowerPoint, Excel.
  • Strong attention to detail.
  • Ability to work independently.

About Mirati Therapeutics

Mirati Therapeutics is a late-stage biotechnology company whose mission is to discover, design and deliver breakthrough therapies to transform the lives of patients with cancer and their loved ones. The company is relentlessly focused on bringing forward therapies that address areas of high unmet need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer. Mirati is using its scientific expertise to develop novel solutions in two registration-enabling programs: adagrasib (MRTX849), an investigational small molecule, potent and selective KRAS G12C inhibitor, as monotherapy and in combination with other agents, and sitravatinib, an investigational spectrum-selective inhibitor of receptor tyrosine kinases in combination with checkpoint inhibitor therapies. Mirati is also advancing its differentiated preclinical portfolio, including MRTX1133, an investigational KRAS G12D inhibitor, and other oncology discovery programs. Unified for patients, Mirati’s vision is to unlock the science behind the promise of a life beyond cancer.

For more information about Mirati Therapeutics, visit us at Mirati.com or follow us on Twitter and LinkedIn.

Why Join?

At Mirati, we have an unapologetic and relentless focus on our mission to transform the lives of patients with cancer and their loved ones. Patients and their families motivate us to work smarter, faster and better. We are driven by the knowledge that our efforts can one-day deliver life-saving therapies for the people who need us most. Urgency, open-mindedness, accountability and collaboration ground our work. These shared values are central to who we are, what we do and how we do it.

Our people fuel our success. They are fearless and passionate in their daily pursuit of our mission. We are committed to continuing to create a company and experience that attracts and keeps the best people. When you want your days to count and the work you do to matter, discovering and delivering potentially life-changing therapies is more than a job, it’s the chance to be part of something bigger.

We believe diverse professional experiences and an inclusive culture can drive better outcomes for patients. We want employees to be authentic and use their perspectives to contribute to our mission in a meaningful way.

Mirati cultivates an environment where:

  • An entrepreneurial attitude is encouraged
  • Our people are empowered to speak up, embrace the gray and achieve solutions
  • Diverse experiences are an important of part making the best decisions
  • We laugh and have fun as a work family

No matter the role, we are unified by our passion for helping patients, and are inspired by a single vision to unlock the science behind the promise of a life beyond cancer. Together, we own Mirati’s success.

Learn more at Mirati.com/careers.

Mirati is an Equal Opportunity Employer (EOE) we celebrate diverse experiences without regard to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic information, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.

1651230

Job Description Summary

This leadership position will be responsible for developing and implementing strategies to support systems integration enhancements for clinical trials. This role requires strategic orientation and functional expertise to lead the team and to develop new approaches to streamline clinical trial processes and conduct. This role will be the single point of accountability for robust clinical trial feasibility and use of analytics to drive and optimize site selection, a vertically integrated organization of dedicated study start-up professionals, vendor management, support of external collaborations, and other functions to facilitate increased operational efficiency. The role will establish the vision and build the framework to support the integration of novel enhancements and analogs to improve clinical trial performance and KPIs. You will develop, implement, and continuously enhance clinical research processes and capabilities to improve the quality and execution of Mirati’s clinical trials. You will play a critical role in the success of Mirati’s strategy to improve efficiencies and enable enhanced process capabilities for the delivery of clinical trials. You will partner with multiple internal groups within Integrative Sciences, Clinical Development, Regulatory Affairs, Pharmacovigilance, Biometrics, Clinical Operations, and Medical Affairs and work cross-functionally with other leaders to ensure systems integration standards meet business needs and objectives as well as regulatory standards.

Your Responsibilities

  • Lead organization in the delivery of high-quality process and operational excellence for clinical trials
  • Establish trial site feasibility and selection processes using advanced analytics and predictive models
  • Lead development of clinical and operational data-driven feasibility estimates, benchmarking assumptions, validated scenarios & accurate planning
  • Develop and optimize processes and procedures for vendor management, clinical trial feasibility, study start-up activities, external collaborations, and clinical trial event management
  • Develop and integrate new technologies, systems, and tools to enhance clinical trial conduct and overall performance
  • Monitor benchmarks with industry peers and across other industries to establish and update best practices and KPIs
  • Partner with CROs, Clinical Operations and Program Management to develop and deliver rapid, accurate, and robust assessments of program and country feasibility, oversight of site identification/site feasibility, and timing of key start-up and recruitment milestones
  • Ensure appropriate communication and involvement across functions to create clear accountability for high quality, multidisciplinary processes
  • Recognize and implement efficiencies identified through process improvements

What is Required

  • Master’s Degree in a scientific discipline. Doctorate degree preferred.
  • At least 15 years of experience in biotech, CRO, academia, or pharmaceutical industry-leading oncology clinical trials
  • Strong background showing progressive clinical trial and clinical development experience, including staff management
  • Demonstrated experience with improving clinical trial KPIs
  • Previous clinical trial outsourcing and associated governance leadership experience
  • Ability to develop new clinical trial strategies using technology and systems (i.e. site feasibility, RWD, analytics etc.)
  • Leadership and or staff experience in a study start up unit and/ or feasibility center of excellence preferred
  • Strong written/verbal communication skills, detail-oriented nature
  • Excellent leadership and influencing skills
  • Demonstrated project management skills
  • Ability to provide direction with cross-functional teams in a matrixed team environment
  • Excellent computer skills including MS Office (Word, Excel, PowerPoint, Outlook)

About Mirati Therapeutics

Mirati Therapeutics is a late-stage biotechnology company whose mission is to discover, design, and deliver breakthrough therapies to transform the lives of patients with cancer and their loved ones. The company is relentlessly focused on bringing forward therapies that address areas of high unmet need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer. Mirati is using its scientific expertise to develop novel solutions in two registration-enabling programs: adagrasib (MRTX849), an investigational small molecule, potent and selective KRAS G12C inhibitor, as monotherapy and in combination with other agents, and sitravatinib, an investigational spectrum-selective inhibitor of receptor tyrosine kinases in combination with checkpoint inhibitor therapies. Mirati is also advancing its differentiated preclinical portfolio, including MRTX1133, an investigational KRAS G12D inhibitor, and other oncology discovery programs. Unified for patients, Mirati’s vision is to unlock the science behind the promise of a life beyond cancer.

For more information about Mirati Therapeutics, visit us at Mirati.com or follow us on LinkedIn.

Why Join?

At Mirati, we have an unapologetic and relentless focus on our mission to transform the lives of patients with cancer and their loved ones. Patients and their families motivate us to work smarter, faster and better. We are driven by the knowledge that our efforts can one-day deliver life-saving therapies for the people who need us most. Urgency, open-mindedness, accountability, and collaboration ground our work. These shared values are central to who we are, what we do, and how we do it.

Our people fuel our success. They are fearless and passionate in their daily pursuit of our mission. We are committed to continuing to create a company and experience that attracts and keeps the best people. When you want your days to count and the work you do to matter, discovering and delivering potentially life-changing therapies is more than a job, it’s the chance to be part of something bigger.

We believe diverse professional experiences and an inclusive culture can drive better outcomes for patients. We want employees to be authentic and use their perspectives to contribute to our mission in a meaningful way.

Mirati cultivates an environment where:

  • An entrepreneurial attitude is encouraged
  • Our people are empowered to speak up, embrace the gray and achieve solutions
  • Diverse experiences are an important of part making the best decisions
  • We laugh and have fun as a work-family

No matter the role, we are unified by our passion for helping patients and are inspired by a single vision to unlock the science behind the promise of a life beyond cancer. Together, we own Mirati’s success.

Learn more at Mirati.com/careers.

Mirati is an Equal Opportunity Employer (EOE) we celebrate diverse experiences without regard to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic information, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.

1666026

Job Description Summary

Mirati is looking for a talented Medical Director to join the Clinical team. The successful candidate will have a passion for novel science, an affinity for strategic thinking, looking beyond the day-to-day execution, and will have a track record of keeping clinical programs on track and hitting milestones. The position will provide key overall clinical, scientific and/or logistical support to clinical development programs and is responsible for the compliance of the program to regulatory standards and procedures and will be graded according to the level of experience of the successful candidate.

Your Responsibilities

  • Clinical leadership of global oncology clinical trials (Phase 1-3), ensuring that studies are carried out in accordance with the clinical development plan, GCPs, ICH and FDA and other regulatory authority requirements.
  • Help identify global study sites and foster relationships with study investigators
  • As the primary medical monitor for assigned study(ies), be the first point of contact with sites; answer site questions about eligibility, enrollment; safety and patient management
  • Chair internal and external clinical trial meetings-updating clinical staff and upper management on patient recruitment, trial issues, investigator’s feedback, patient enrollment issues and presenting a plan of action for resolution of issues
  • Production of clinical documents required for the conduct of clinical studies, such as clinical protocols (and amendments as needed), informed consent documents, investigator’s brochures, and safety management plans in compliance with regulations and good clinical practices
  • Preparation of abstracts and posters for scientific meetings
  • Preparation of slides/ presentation at internal and external meetings, such as team meetings, Advisory Boards and Board of Director Meetings
  • Lead ongoing data interpretation to understand safety and efficacy profile of the investigational drug
  • Assist in preparation of clinical sections of key regulatory documents, e.g., IND annual reports and briefing packages
  • Present aspects of clinical program at Site Initiation Visits, Investigator’s Meetings and scientific conferences
  • Maintain state-of-the-art knowledge of the principles and theory in relevant therapeutic areas
  • Assist in case report form (CRF) development and data analysis plans
  • Review project specifications for IRT/IXRS, ePRO, Imaging Charter for Central radiology review and other procedural documents
  • Perform in data cleaning and clinical study report review
  • Review and approve study materials such as CRFs, patient diaries, drug accountability forms, study reference manuals
  • Assist in generation and update of Clinical Development Plan (CDP)
  • Perform all duties in keeping with the Company’s core values, policies and all applicable regulations.

What is Required

  • Medical Doctor (M.D.), either with Board Certification in Medical Oncology/ Hematology Oncology or Internal Medicine
  • 5+ years of clinical development experience in the pharmaceutical or biotechnology industries with at least 2 years involvement in oncology drug development
  • Thorough working knowledge / understanding of clinical trial design, methodology and statistical concepts.
  • Phase IIII oncology clinical trial experience preferred.
  • Working knowledge of the IND/NDA process preferred.
  • In-depth knowledge of GCP/ICH guidelines preferred.
  • Proven ability to interact with different functional groups, investigators, key opinion leaders and the medical/scientific community.
  • Available for ~ 25% travel, including overnight stays.
  • Strong written and verbal communication skills required.
  • Ability to thrive in a fast-paced, dynamic small company environment with ability to adjust workload based upon changing priorities.
  • Leadership skills including a collaborative and team-oriented approach.
  • Good organizational, time management and interpersonal skills.
  • Demonstrated excellence in management skills, with track record of successfully managing multiple projects, trials, and priorities.
  • Ability to work well with global, multi-disciplinary teams.

About Mirati Therapeutics

Mirati Therapeutics is a late-stage biotechnology company whose mission is to discover, design and deliver breakthrough therapies to transform the lives of patients with cancer and their loved ones. The company is relentlessly focused on bringing forward therapies that address areas of high unmet need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer. Mirati is using its scientific expertise to develop novel solutions in two registration-enabling programs: adagrasib (MRTX849), an investigational small molecule, potent and selective KRAS G12C inhibitor, as monotherapy and in combination with other agents, and sitravatinib, an investigational spectrum-selective inhibitor of receptor tyrosine kinases in combination with checkpoint inhibitor therapies. Mirati is also advancing its differentiated preclinical portfolio, including MRTX1133, an investigational KRAS G12D inhibitor, and other oncology discovery programs. Unified for patients, Mirati’s vision is to unlock the science behind the promise of a life beyond cancer.

For more information about Mirati Therapeutics, visit us at Mirati.com or follow us on Twitter and LinkedIn.

Why Join?

At Mirati, we have an unapologetic and relentless focus on our mission to transform the lives of patients with cancer and their loved ones. Patients and their families motivate us to work smarter, faster and better. We are driven by the knowledge that our efforts can one-day deliver life-saving therapies for the people who need us most. Urgency, open-mindedness, accountability and collaboration ground our work. These shared values are central to who we are, what we do and how we do it.

Our people fuel our success. They are fearless and passionate in their daily pursuit of our mission. We are committed to continuing to create a company and experience that attracts and keeps the best people. When you want your days to count and the work you do to matter, discovering and delivering potentially life-changing therapies is more than a job, it’s the chance to be part of something bigger.

We believe diverse professional experiences and an inclusive culture can drive better outcomes for patients. We want employees to be authentic and use their perspectives to contribute to our mission in a meaningful way.

Mirati cultivates an environment where:

  • An entrepreneurial attitude is encouraged
  • Our people are empowered to speak up, embrace the gray and achieve solutions
  • Diverse experiences are an important of part making the best decisions
  • We laugh and have fun as a work family

No matter the role, we are unified by our passion for helping patients, and are inspired by a single vision to unlock the science behind the promise of a life beyond cancer. Together, we own Mirati’s success.

Learn more at Mirati.com/careers.

Mirati is an Equal Opportunity Employer (EOE) we celebrate diverse experiences without regard to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic information, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.

1724973

Job Description Summary

The Clinical Operations Study Lead will lead study operational strategy and planning, and oversee execution of clinical studies for assigned clinical program(s), supporting clinical strategy defined in Clinical Development Plan

  • Oversee the execution of studies in assigned clinical program(s) in compliance with quality standards (including ICH GCP, local regulations and Mirati SOPs), on schedule and on budget
  • Lead, direct and oversee CROs and other 3rd party vendors to achieve project goals

Your Responsibilities

Leading Operational Strategy, Planning and Execution of assigned Clinical Trials

  • Provides leadership, direction and oversight to CRO and 3rd party vendors to ensure study is progressing per plan and study issues are addressed and brought to resolution
  • Develops Operational Strategy with a focus on ensuring accurate assumptions are applied and robust risk management plans are in place, and periodically updated during the life of the study
  • Leads cross functional Study Team Meeting
  • Single point of operational accountability for entire study lifecycle from protocol synopsis to CSR
  • Presents at Quarterly Reviews with CRO and Mirati Leadership reviewing performance against metrics and other key performance indicators (KPIs)
  • Provides subject matter expertise and operational input into protocol synopsis, final protocol and other study related documents
  • Ensures operational feasibility, patient and site, is conducted
  • Contributes to CRO selection; Ensures CRO/3rd party vendors are appropriately onboarded, trained and qualified
  • Participates in country and site feasibility/selection process, with a focus on providing country operational insights, corporate alignment and therapeutic expertise to ensure alignment between study execution plan and program strategy
  • Accountable for study budget planning and management
  • Validates study budget and ensures impacts are adequately addressed
    • Provides alternative options/offsets in the case of significant budget increases
  • Routinely communicates study status, issues and mitigation plans to manager and project team

CRO OVERSIGHT:

  • Review and approval of key monitoring documents/plans, periodic review of outputs, decisions and actions related to monitoring
  • Review, endorsement and validation of relevant study plans and timelines
  • Attendance at CRO-led study meetings; Drive agenda topics and review meeting minutes for accuracy and compliance
  • Review of outcomes/actions related to protocol deviations; primary purpose of review is to support the identification of trends across sites and/or the study
  • Documented review and monitoring of issues, risks and decisions at the study level and implementation of appropriate mitigation strategies
  • In partnership with data management, review and pressure test all database timelines and plans; ensure strong linkage between the strategy (i.e., filing/registration, data generation, etc.) with the operational plan for database lock and CSR
  • Ensure studies are “inspection ready” at all times; May be involved in regulatory inspections by preparing for and/or attending the inspections

What is Required

  • Bachelor’s degree in one of the disciplines related to drug development or business required; Advanced degree desirable
  • Minimum 8 years of relevant experience
  • Broad experience in a Clinical Trial discipline executing all phases of a study from protocol synopsis to CSR
  • Demonstrated project management and cross-functional team leadership experience
  • Experience in understanding of key drivers impacting budgets and experience building a Clinical Trial Budget and managing project to budget
  • Strategic thinking and targeted problem-solving skills
  • Ability to identify, resolve & escalate issues
  • Ability to leverage negotiation and conflict resolution skills to enhance team performance and delivery
  • Ability to represent & communicate clearly to senior leaders, governance and external bodies
  • Strong communication and interpersonal skills

About Mirati Therapeutics

Mirati Therapeutics is a late-stage biotechnology company whose mission is to discover, design and deliver breakthrough therapies to transform the lives of patients with cancer and their loved ones. The company is relentlessly focused on bringing forward therapies that address areas of high unmet need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer. Mirati is using its scientific expertise to develop novel solutions in two registration-enabling programs: adagrasib (MRTX849), an investigational small molecule, potent and selective KRAS G12C inhibitor, as monotherapy and in combination with other agents, and sitravatinib, an investigational spectrum-selective inhibitor of receptor tyrosine kinases in combination with checkpoint inhibitor therapies. Mirati is also advancing its differentiated preclinical portfolio, including MRTX1133, an investigational KRAS G12D inhibitor, and other oncology discovery programs. Unified for patients, Mirati’s vision is to unlock the science behind the promise of a life beyond cancer.

For more information about Mirati Therapeutics, visit us at Mirati.com or follow us on LinkedIn.

Why Join?

At Mirati, we have an unapologetic and relentless focus on our mission to transform the lives of patients with cancer and their loved ones. Patients and their families motivate us to work smarter, faster and better. We are driven by the knowledge that our efforts can one-day deliver life-saving therapies for the people who need us most. Urgency, open-mindedness, accountability and collaboration ground our work. These shared values are central to who we are, what we do and how we do it.

Our people fuel our success. They are fearless and passionate in their daily pursuit of our mission. We are committed to continuing to create a company and experience that attracts and keeps the best people. When you want your days to count and the work you do to matter, discovering and delivering potentially life-changing therapies is more than a job, it’s the chance to be part of something bigger.

We believe diverse professional experiences and an inclusive culture can drive better outcomes for patients. We want employees to be authentic and use their perspectives to contribute to our mission in a meaningful way.

Mirati cultivates an environment where:

  • An entrepreneurial attitude is encouraged
  • Our people are empowered to speak up, embrace the gray and achieve solutions
  • Diverse experiences are an important of part making the best decisions
  • We laugh and have fun as a work family

No matter the role, we are unified by our passion for helping patients, and are inspired by a single vision to unlock the science behind the promise of a life beyond cancer. Together, we own Mirati’s success.

Learn more at Mirati.com/careers.

Mirati is an Equal Opportunity Employer (EOE) we celebrate diverse experiences without regard to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic information, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.

1731872

Job Description Summary

The Manager, Medical Coding (Data Management) is responsible for performing medical coding, creating internal coding guidelines and processes, and managing medical dictionaries. This individual will work with the Medical Directors, Clinical Development Scientists, and Pharmacovigilance to ensure accurate and consistent coding for clinical data deliverables. These activities help to ensure high quality data is achieved in support of analysis for regulatory submissions, safety monitoring and publications.

Your Responsibilities

  • Performs accurate and consistent medical coding of clinical trial data per MedDRA and WHODrug, and issues queries in EDC as needed
  • Manages coding deliverables across clinical studies/programs and ensures coding reviews are completed with respect to overall study timelines
  • Develops and implements internal coding conventions, SOPs, guidelines, and processes; ensures adherence to industry standards
  • Defines and develops coding review listings in collaboration with Clinical Programming Leads
  • Works with the System Administrator to set up and maintain the coding tool/application, and participates in user acceptance testing
  • Manages the up-versioning of coded terms, as applicable
  • For outsourced studies, performs quality oversight of external vendors who are performing coding, and reviews their documentation and processes
  • Participates in the development and implementation of process improvements to support the collection, integration, monitoring, review, and reporting of data
  • Manages coding dictionary versions and subscriptions
  • Proactively identifies potential study issues/risks and recommends/implements solutions

What is Required

  • Bachelor’s degree (at a minimum) in a life science or health related field preferred
  • 6+ years of Medical Coding experience in the CRO, pharmaceutical or biotechnology industry
  • Expertise with MedDRA and WHODrug
  • Experience coding in Medidata Rave Coder preferred
  • Experience with EDC systems is required
  • Experience coding in oncology Phase I, II, and III studies preferred
  • Knowledge of industry standards, ICH guidelines, and regulatory requirements
  • Proven ability to work both independently and in a team setting

About Mirati Therapeutics

Mirati Therapeutics is a late-stage biotechnology company whose mission is to discover, design and deliver breakthrough therapies to transform the lives of patients with cancer and their loved ones. The company is relentlessly focused on bringing forward therapies that address areas of high unmet need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer. Mirati is using its scientific expertise to develop novel solutions in two registration-enabling programs: adagrasib (MRTX849), an investigational small molecule, potent and selective KRAS G12C inhibitor, as monotherapy and in combination with other agents, and sitravatinib, an investigational spectrum-selective inhibitor of receptor tyrosine kinases in combination with checkpoint inhibitor therapies. Mirati is also advancing its differentiated preclinical portfolio, including MRTX1133, an investigational KRAS G12D inhibitor, and other oncology discovery programs. Unified for patients, Mirati’s vision is to unlock the science behind the promise of a life beyond cancer.

For more information about Mirati Therapeutics, visit us at Mirati.com or follow us on LinkedIn.

Why Join?

At Mirati, we have an unapologetic and relentless focus on our mission to transform the lives of patients with cancer and their loved ones. Patients and their families motivate us to work smarter, faster and better. We are driven by the knowledge that our efforts can one-day deliver life-saving therapies for the people who need us most. Urgency, open-mindedness, accountability and collaboration ground our work. These shared values are central to who we are, what we do and how we do it.

Our people fuel our success. They are fearless and passionate in their daily pursuit of our mission. We are committed to continuing to create a company and experience that attracts and keeps the best people. When you want your days to count and the work you do to matter, discovering and delivering potentially life-changing therapies is more than a job, it’s the chance to be part of something bigger.

We believe diverse professional experiences and an inclusive culture can drive better outcomes for patients. We want employees to be authentic and use their perspectives to contribute to our mission in a meaningful way.

Mirati cultivates an environment where:

  • An entrepreneurial attitude is encouraged
  • Our people are empowered to speak up, embrace the gray and achieve solutions
  • Diverse experiences are an important of part making the best decisions
  • We laugh and have fun as a work family

No matter the role, we are unified by our passion for helping patients, and are inspired by a single vision to unlock the science behind the promise of a life beyond cancer. Together, we own Mirati’s success.

Learn more at Mirati.com/careers.

Mirati is an Equal Opportunity Employer (EOE) we celebrate diverse experiences without regard to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic information, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.

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