Management Team


Charles M. Baum, MD, PhD

Dr. Baum was appointed President and Chief Executive Officer and Board Member of Mirati Therapeutics in November 2012. Since then, he has been responsible for moving the company to the United States, listing the company on NASDAQ and establishing its headquarters in San Diego, California. In addition, he has built a world class precision oncology leadership team and transformed Mirati into a company focused on the innovative, targeted development of Mirati’s receptor tyrosine kinase and histone deacetylase inhibitors in various cancers.

Prior to joining Mirati he was Senior Vice President for Biotherapeutic Clinical Research within Pfizer’s Worldwide Research & Development division. Dr. Baum was at Pfizer from 2003 until joining Mirati in 2012, serving in roles of increasing responsibility including as Vice President and Head of Oncology Development and as Chief Medical Officer for Pfizer’s Biotherapeutics and Bioinnovation Center. He was responsible for the development of the oncology portfolio, including Axitinib (Inlyta®), Crizotinib (Xalkori®) and the approval of sunitinib (Sutent®) for the treatment of gastrointestinal stromal tumor (GIST) and renal cell carcinoma. Prior to joining Pfizer, Dr. Baum was responsible for the Phase I-IV development of several oncology compounds at Schering-Plough, including temozolomide (Temodar®) which was approved for the treatment of patients with advanced brain tumors.

His career has included academic and hospital positions at Stanford and Emory universities, as well as positions of increasing responsibility within the pharmaceutical industry (Systemix, Searle, Schering-Plough and Pfizer). Dr. Baum currently serves on the board of directors of Array BioPharma. Dr. Baum received his M.D. and Ph.D. (Immunology) degrees from Washington University School of Medicine in St. Louis, Missouri and completed his post-graduate training at Stanford University, California. Dr. Baum has received research support from the National Institutes of Health and the American Cancer Society, published more than 50 peer-reviewed manuscripts, and holds a number of patents and patent applications.


Allen Albright, PhD

Allen Albright, PhD joined Mirati as Head of Regulatory Affairs in 2014 and was named Vice President of Regulatory Affairs and Quality Assurance in 2019. He has over 20 years of experience in Regulatory Affairs including prior positions of increasing responsibility at FDA as well as various large and small companies, including Amgen, Baxter, Agensys (acquired by Astellas), Anadys Pharmaceuticals (acquired by Roche), and Halozyme. His regulatory experience includes full product life cycle management and oversight (PreIND, NDA/BLA, and Post-Approval) with focus on oncology drug development.

Dr. Albright holds a PhD in Microbiology & Immunology from the Uniformed Services University of the Health Sciences (Bethesda, MD) and completed post-doctoral research at the Johns Hopkins University School of Medicine (Baltimore, MD).


Isan Chen, MD

Isan Chen, MD is board certified in internal medicine, hematology and medical oncology with more than 15 years of experience in oncology and clinical trials from first-in-humans through global studies designed to support regulatory registration. He has experience in oncology clinical development and interactions with regulatory agencies in the US and Europe. He was most recently the Chief Medical Officer of Aragon Pharmaceuticals which was acquired by Johnson & Johnson in July of 2013. At Aragon, Dr. Chen was responsible for the clinical development strategy of all the company’s programs, including prostate and breast cancer. Prior to Aragon, Dr. Chen served as Vice President of Tumor Strategy in the oncology business unit at Pfizer. In addition he was the clinical lead for sunitinib (Sutent®), a multiple kinase inhibitor, for the treatment of renal cell carcinoma, an indication in which the drug secured FDA approval in 2006. He was also the clinical lead for the Phase I studies of crizotinib (Xalkori®) and CDK 4/6 inhibitor palbociclib.

Dr. Chen completed his hematology/oncology fellowship at University of California, San Diego. Before joining Pfizer, Dr. Chen practiced medicine as a staff physician at City of Hope Medical Center and later as an assistant professor at the University of Texas, M.D. Anderson Cancer Center.


James G. Christensen, PhD

Dr. Christensen joined Mirati in June 2013. In his role at Mirati, he is responsible for drug discovery, translational research, drug manufacturing and companion diagnostics research and teams. While at Mirati, Dr. Christensen led activities related to the discovery and advancement of the KRAS G12C inhibitor, MRTX849, as well as the spectrum-selective receptor tyrosine kinase (RTK) inhibitor, sitravatinib, through IND and clinical development. Prior to Mirati, Dr. Christensen most recently was the head of Oncology Precision Medicine and member of the executive leadership team in the Oncology Research Unit at Pfizer. He joined Pfizer in 2003 and his responsibilities included leading nonclinical research and translational sciences efforts for oncology programs including sunitinib (Sutent®) and crizotinib (Xalkori®). Prior to his time at Pfizer, he held positions at SUGEN/Pharmacia as a Group Leader on the Preclinical Research and Exploratory Development team where he was responsible for leadership of c-Met and erbB family preclinical development programs and aspects of research and development for sunitinib. Dr. Christensen initiated his industry experience at Warner Lambert/Parke-Davis with research focus in RTK biology and pathway biomarker development in the oncology therapeutic area. He has authored or co-authored over 140 peer-reviewed research articles in scientific journals including Science, Nature, Cancer Cell, Cancer Discovery, New England Journal of Medicine and others. In addition, he also participates on the editorial boards for Cancer Research and Molecular Cancer Therapeutics and is a member of the Scientific Advisory panel at Bridge Bio/QED.

Dr. Christensen received his PhD degree focusing in Molecular Pharmacology from North Carolina State University with dissertation research directed toward characterization of mechanisms of apoptosis dysregulation during the process of carcinogenesis.


Jamie Donadio

Mr. Donadio has served as our Senior Vice President and Chief Financial Officer since March 2016 and served as our Vice President, Finance from March 2013 through March 2016. Mr. Donadio holds more than 20 years of experience in finance and accounting, including over 15 years in the life sciences industry.

Prior to joining Mirati, Mr. Donadio was at Amylin Pharmaceuticals from April 2001 through January 2013 where he held a number of corporate finance and accounting roles of increasing responsibility, most recently serving as Senior Director of Finance. Prior to Amylin, Mr. Donadio held roles with Novatel Wireless, Inc. and Ernst & Young LLP.

Mr. Donadio holds a B.S. in Accounting from Babson College and is a certified public accountant (inactive) in the State of California.


Jenny Gizzi

Jenny Gizzi joined Mirati in 2019 as Vice President and Head of Human Resources, bringing more than 20 years of experience from all facets of HR in the biotech and pharmaceutical sectors. In her most recent role as Head of Strategy & Operations, Business Insights and Analytics at Bristol-Myers Squibb, a global pharmaceutical company, she spent much of her time working on the Celgene acquisition and integration. Additionally, she served as Head of Human Resources, supporting the early Oncology Research site for the Bay Area and Cambridge, MA locations. At the Cambridge location, she was responsible for opening BMS’s newest research site. Other roles included Head of Global Talent for European Markets, Australia and Canada where she oversaw global talent for eight markets and 13 countries and led the international team specializing in strategy creation overseeing all talent.

Prior to BMS, Jenny held roles of increasing responsibility at llumina, Inc. where she was ultimately responsible for their global talent function as the Head of Global Talent Acquisition. Jenny has been a welcomed speaker at multiple global conferences where she shares her strategy on how to execute talent plans to engage, retain and develop amazing talent. Jenny’s background also includes roles at other pharmaceutical companies, including Aventis (now Sanofi) as well as other sectors of the telecommunications industry. Jenny firmly believes “talent is everything – it’s what sets us apart and makes us different from everyone else.”
Jenny holds a BA in Corporate Communications from Farleigh-Dickinson University in NJ.


Perry C. Johnston

Mr. Johnston joined Mirati as an employee in February 2014 having previously supported the company in a consulting capacity commencing in July 2013. With more than twenty years of in-house experience, Mr. Johnston has served on senior leadership teams and helped build and lead legal, compliance, regulatory and risk management functions. From August 2009 to July 2013, Mr. Johnston served as Senior Director of Legal at Amylin Pharmaceuticalas, Inc. where he led the Transactions/Contracts Group and managed legal support for the Corporate Development, Business Development, and Alliance Management functions. Prior to joining Amylin, Mr. Johnston served in senior leadership roles with various biotechnology, health provider, and medical device companies, including as Vice President, General Counsel and Company Secretary at Advanced BioEnergy LLC, Vice President of Legal, Regulatory and Compliance at Aperio Technologies, Inc., Vice President, General Counsel and Corporate Secretary at the Nevada Cancer Institute, Vice President of Legal and Compliance at CardioNet, Inc., and Senior Legal Counsel at Medtronic, Inc. Mr. Johnston worked as an attorney in private practice for several years and began his career after law school in the tax field, working with both Coopers & Lybrand in Minneapolis and KPMG Peat Marwick in San Diego.

Mr. Johnston received his Juris Doctor degree from the University of Minnesota Law School and his B.S. Business Administration (finance and economics emphasis) from the University of Minnesota School of Management.


Chris LeMasters

Mr. LeMasters joined Mirati in October 2016. Prior to joining Mirati, Mr. LeMasters served as the CEO of Promosome, a privately held biotherapeutics and synthetic biology company. Previously, Mr. LeMasters held senior management positions at several biotherapeutics companies, most recently as co-founder and chief business officer of Tragara Pharmaceuticals, a clinical-stage cancer therapeutics company. Mr. LeMasters also served as co-founder and chief business officer of Cabrellis Pharmaceuticals, Inc., where he negotiated its acquisition by Pharmion Corporation for $104 million, and as vice president, corporate development of Conforma Therapeutics, where he negotiated its acquisition by Biogen IDEC for $250 million. Mr. LeMasters also worked in the corporate business development group at Eli Lilly & Company and was responsible for the successful negotiation of numerous partnerships and licenses across a range of therapeutic areas. Earlier in his career, he was a management consultant with Coopers & Lybrand Consulting and an operational auditor with Owens Corning.

Mr. LeMasters currently serves as a board member of Aarden Pharmaceuticals, where he is also a co-founder, and as a board member of the Hoosier Cancer Research Network, a clinical research organization. He received a B.S. degree in Finance from Indiana University and an MBA with honors from the University of Chicago.


Matthew Marx, PhD

Dr. Marx joined Mirati in 2016 bringing over 23 years of post-Ph.D. experience in chemistry and drug discovery. Currently Vice President and head of Drug Discovery at Mirati Therapeutics, he is responsible for the creation and progression of small molecules to advance the Mirati research portfolio, overseeing synthetic and medicinal chemistry, structural biology, molecular modeling and DMPK. Prior to Mirati, Dr. Marx led the chemistry department at Takeda California, advancing medicinal chemistry efforts across oncology, immunology and metabolic diseases projects as a member of the site senior leadership team, the global chemistry leadership team and the global oncology research leadership team. Dr. Marx began his industry career in the oncology research group at Pfizer, where he worked in roles of escalating responsibility at the Groton, CT site, ultimately leading that therapeutic area chemistry group. As a project member, team leader or department head, he has been responsible for the nomination of many small-molecule development candidates and ten investigational new drugs (IND).

Dr. Marx was the Medicinal Chemistry Gordon Conference Chair in 2017 and has been active in the Chemistry in Cancer Research (CICR) working group of the American Association for Cancer Research (AACR), serving as an abstract reviewer, program committee member and CICR Steering Committee Member. Additionally, over the course of 4 years served as the Co-Chair of the Drugs on the Horizon symposium.

Dr. Marx earned his B.S. and Ph.D. degrees at the University of California, Berkeley, and was an NIH post-doctoral fellow at the University of Texas, Austin.


Vickie Reed

Ms. Reed joined Mirati in October 2013 and was named Vice President of Finance in December 2016. Previously, she served as Senior Director of Finance and Controller at Zogenix, Inc., a biotechnology company in Emeryville, California. From September 2009 to November 2012 Ms. Reed held corporate accounting positions at Amylin Pharmaceuticals, Inc., most recently serving as Director SEC Reporting and Revenue Accounting. Prior to joining Amylin, Ms. Reed held financial roles at several biotechnology and telecommunications companies.

Ms. Reed began her career with Price Waterhouse, now PricewaterhouseCoopers, in Denver, Colorado. Ms. Reed is a Certified Public Accountant in the State of Colorado, and received a B.S. in Accounting from University of Colorado Denver.


Philip Roberts

Mr. Roberts joined Mirati in May 2019 with over 25 years of experience in pharmaceutical development, manufacturing science and technology, and operations. He has a record of building high performing organizations and transforming development-stage companies into successful commercial enterprises. Phil was most recently Head of Pharmaceutical Development and Technical Operations at Avanir Pharmaceuticals where he was responsible for providing strategic, operational leadership and oversight for the drug product development. Prior to that he was Senior Vice President of Technical Operations at Orexigen where he held global responsibility for pharmaceutical product development, manufacturing and supply chain operations. He has held diverse technical and operations management positions at Exelixis, Nektar, Pfizer, Roche and Eli Lilly and has successfully developed and commercialized novel pharmaceutical products, including CONTRAVE®/MYSIMBA®, COMETRIQ®, EXUBERA® and VIRACEPT®. Mr. Roberts received his M.S. in Chemical Engineering from Louisiana State University and a B.S. in Chemical Engineering from Rensselaer Polytechnic Institute.


Vanessa Tassell

Ms. Tassell joined Mirati in October 2013 and was named Vice President of Clinical Science in October 2017. She has more than 20 years of experience in clinical drug development. Prior to joining Mirati, she was Senior Director of Clinical Development at Aragon Pharmaceuticals located in San Diego. At Aragon, she managed the apalutamide (ERLEADA™) program while it was in development and prior to the Aragon acquisition by Johnson & Johnson in 2013. Ms. Tassell’s experience includes positions of increasing responsibility at Pfizer from 2000-2013, which involved supporting clinical development activities for oncology programs including NDA submissions for sunitinib (SUTENT®) and crizotinib (XALKORI®). Ms. Tassell started her career with Parexel International in Boston, Massachusetts.

Ms. Tassell has a B.S. degree in Psychology from Northeastern University, Massachusetts.