Mr. Grey currently serves as Executive Chairman of Mirum Pharmaceuticals Inc. and served previously as chief executive officer from the company’s inception in May 2018 to March 2019. Mr. Grey has served as executive chairman of Amplyx Pharmaceuticals, Inc. since January 2017; Reneo Pharmaceuticals, Inc. since December 2017; and Spruce Biosciences, Inc, since April 2017. He has also served as a venture partner at Pappas Ventures since January 2010, served from October 2015 to January 2017 as the president and chief executive officer of Amplyx, and from September 2014 to December 2017 as chairman and chief executive officer of Reneo. He previously served as President and Chief Executive Officer of Lumena Pharmaceuticals, Inc., a privately-held biotechnology company before it was acquired by Shire. Between January and September 2009, he served as President and Chief Executive Officer of Auspex Pharmaceuticals, Inc., a private biotechnology company. From January 2005 until its acquisition in August 2008, Mr. Grey was President and Chief Executive Officer of SGX Pharmaceuticals, Inc., a public biotechnology company, where he previously served as President from June 2003 to January 2005 and as Chief Business Officer from April 2001 until June 2003. Prior to joining SGX Pharmaceuticals, Inc., Mr. Grey acted as President, Chief Executive Officer and Board member of Trega Biosciences, Inc., a biotechnology company. From November 1994 to August 1998, Mr. Grey was the President of BioChem Therapeutic, Inc., the pharmaceutical operating division of BioChem Pharma, Inc. During 1994, Mr. Grey served as President and Chief Operating Officer for Ansan, Inc., a pharmaceutical company. From 1974 to 1993, he served in various roles with Glaxo, Inc. and Glaxo Holdings, plc, culminating in the position of Vice President, Corporate Development. Mr. Grey is currently a director of Horizon Pharma, plc. and BioMarin Pharmaceutical, Inc., public pharmaceutical companies. He received a B.Sc. in chemistry from the University of Nottingham, United Kingdom.